As Reuters reports, scientists at the University of Minnesota are attempting to determine whether the drug can prevent the virus from causing severe symptoms and perhaps even prevent the rapid multiplication of the virus within the body. Children aged 6 years and older can take it, but only to treat high blood pressure. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Thus far, our response to the pandemic has been to test symptomatic people and issue lockdowns and quarantines while advising social distancing to even those who appear healthy. SPH biostatistics researchers are leading the design, conduct, and data analysis of studies to see if losartan can … We comply with the HONcode standard for trustworthy health information -, https://www.cebm.net/covid-19/angiotensin-converting-enzyme-ace-inhibitors-and-angiotensin-receptor-blockers-in-covid-19/, https://doi.org/10.1016/S2213-2600(20)30153-3. Antihypertensive drugs and risk of COVID-19? Losartan can be taken by adults aged 18 years and over. Mice treated with losartan after an acid-induced lung injury and exposed to the SARS virus had less lung injury and fluid around their lungs than mice treated with placebo, Losartan, in addition to infusions of angiotensin-2, prevented severe lung injury and edema in mice that had had all their ACE-2 removed, Recombinant ACE2 infusions have improved lung injury in people with SARS, Acute respiratory distress syndrome secondary to reduced ACE2 activity has been observed in other viral pneumonias, such as H5N1 and H7N9 influenza, Mice given losartan after infection with H5N1 influenza had reduced lung edema and an increased rate of survival. For people already taking losartan or any other ARB, the advice from the medical community is to keep taking it unless your doctor tells you otherwise. The Lancet. School of Public Health and Medical School researchers are conducting two new studies to see if losartan can protect the lungs of COVID-19 patients. Formulation: Tablet: 25 mg, 50 mg, 100 mg. The research was based on the theory that inhibition of an overactive RAS might increase the risk of pulmonary complications from viral infections. Losartan does not block the virus causing COVID-19, called SARS-CoV-2, but it may reduce the activity of the renin-angiotensin system, which is overactive in people with high blood pressure, which may increase their risk of developing lung complications from COVID-19. Losartan and other blood pressure medicines can lower blood pressure to dangerous levels or damage the kidneys. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Does Zinc protect you from Covid-19 or boost your immune system? Can Ivermectin be used to treat COVID-19 (coronavirus)? Age greater than or equal to 18 years of age. Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers in COVID-19. It needs to do RCTs to prove it. Side Effects. Tignanelli, C, Ingraham N, Sparks M, et al. Losartan has attracted interest from the medical community because losartan was used in some preclinical studies to determine its effectiveness against the SARS virus that first appeared in 2002. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The researchers hope this will counteract the effects of the excess angiotensin II and prevent lung damage in COVID-19 patients. Heart Drugs Show Promise With Covid-19 Complications Widely prescribed cardiovascular drugs, some recently suspected in high death rates of infected patients, now … That hormone constricts your blood vessels, increases blood pressure, and causes your body to retain more fluid. 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